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SigProfilerMatrixGenerator

SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations from whole-genome sequencing, whole-exome sequencing, and targeted sequencing data.

Prerequisites

  • Internet Connection
  • Python - v3.4+
  • pandas - any version (automatically installed with SigProfilerMatrixGenerator)
  • Wget - v1.9
  • SigProfilerPlotting - latest version (automatically installed with SigProfilerMatrixGenerator)
  • Reference genomes - At least one reference genome file must be downloaded and installed prior to use

Upgrades

If there is an updated version of the tool, use the following command:

pip install SigProfilerMatrixGenerator --upgrade

Contact

For questions or issues, please contact: contact@sigprofilersuite.org

Citation

If you use SigProfilerMatrixGenerator in your research, please cite the appropriate publication.